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Real-time PCR detection of protein analytes with conformation-switching aptamers

We have developed a novel method that utilizes conformation-switching aptamers for real-time PCR analysis of protein analytes. The aptamers have been designed so that they assume one secondary structure in the absence of a protein analyte, and a different secondary structure in the presence of a pro...

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Bibliografski detalji
Glavni autori: Yang, Litao, Ellington, Andrew D.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544626/
https://ncbi.nlm.nih.gov/pubmed/18541130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2008.05.018
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