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Mapping L1 Ligase ribozyme conformational switch
L1 Ligase (L1L)molecular switch is an in vitro optimized synthetic allosteric ribozyme that catalyzes the regioselective formation of a 5’-to-3’ phosphodiester bond, a reaction for which there is no known naturally occurring RNA catalyst. L1L serves as a proof of principle that RNA can catalyze a cr...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3509952/ https://ncbi.nlm.nih.gov/pubmed/22771572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.06.035 |
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