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Mapping L1 Ligase ribozyme conformational switch

L1 Ligase (L1L)molecular switch is an in vitro optimized synthetic allosteric ribozyme that catalyzes the regioselective formation of a 5’-to-3’ phosphodiester bond, a reaction for which there is no known naturally occurring RNA catalyst. L1L serves as a proof of principle that RNA can catalyze a cr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Giambaşu, George M., Lee, Tai-Sung, Scott, William G., York, Darrin M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509952/
https://ncbi.nlm.nih.gov/pubmed/22771572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.06.035
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