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Characterization of the Structure and Dynamics of the HDV Ribozyme at Different Stages Along the Reaction Path

The structure and dynamics of the hepatitis delta virus ribozyme (HDVr) are studies using molecular dynamics simulations at several stages along its catalytic reaction path, including reactant, activated precursor, transition state mimic and product states, departing from an initial structure based...

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Hlavní autoři: Lee, Tai-Sung, Giambaşu, George, Harris, Michael E., York, Darrin M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244300/
https://ncbi.nlm.nih.gov/pubmed/22200005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jz201106y
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