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Direct selection for ribozyme cleavage activity in cells

Selection may prove to be a powerful tool for the generation of functional RNAs for in vivo genetic regulation. However, traditional in vitro selection schemes do not mimic physiological conditions, and in vivo selection schemes frequently use small pool sizes. Here we describe a hybrid in vitro/in...

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Detaylı Bibliyografya
Asıl Yazarlar: Chen, Xi, Denison, Lisa, Levy, Matthew, Ellington, Andrew D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764470/
https://ncbi.nlm.nih.gov/pubmed/19776159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1635209
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