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Direct selection for ribozyme cleavage activity in cells
Selection may prove to be a powerful tool for the generation of functional RNAs for in vivo genetic regulation. However, traditional in vitro selection schemes do not mimic physiological conditions, and in vivo selection schemes frequently use small pool sizes. Here we describe a hybrid in vitro/in...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2764470/ https://ncbi.nlm.nih.gov/pubmed/19776159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1635209 |
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