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Molecular Evolution of Adeno-associated Virus for Enhanced Glial Gene Delivery
The natural tropism of most viral vectors, including adeno-associated viral (AAV) vectors, leads to predominant transduction of neurons and epithelia within the central nervous system (CNS) and retina. Despite the clinical relevance of glia for homeostasis in neural tissue, and as causal contributor...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2788045/ https://ncbi.nlm.nih.gov/pubmed/19672246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.184 |
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