Directed Evolution of Adeno-associated Virus for Enhanced Gene Delivery and Gene Targeting in Human Pluripotent Stem Cells

Efficient approaches for the precise genetic engineering of human pluripotent stem cells (hPSCs) can enhance both basic and applied stem cell research. Adeno- associated virus (AAV) vectors are of particular interest for their capacity to mediate efficient gene delivery to and gene targeting in vari...

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Главные авторы: Asuri, Prashanth, Bartel, Melissa A, Vazin, Tandis, Jang, Jae-Hyung, Wong, Tiffany B, Schaffer, David V
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2012
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277219/
https://ncbi.nlm.nih.gov/pubmed/22108859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.255
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