An Evolved Adeno-associated Viral Variant Enhances Gene Delivery and Gene Targeting in Neural Stem Cells

Gene delivery to, and gene targeting in, stem cells would be a highly enabling technology for basic science and biomedical application. Adeno-associated viral (AAV) vectors have demonstrated the capacity for efficient delivery to numerous cells, but their application to stem cells has been limited b...

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Main Authors: Jang, Jae-Hyung, Koerber, James T, Kim, Jung-Suk, Asuri, Prashanth, Vazin, Tandis, Bartel, Melissa, Keung, Albert, Kwon, Inchan, Park, Kook In, Schaffer, David V
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070092/
https://ncbi.nlm.nih.gov/pubmed/21224831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.287
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