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Directed Evolution of Adeno-associated Virus for Enhanced Gene Delivery and Gene Targeting in Human Pluripotent Stem Cells

Efficient approaches for the precise genetic engineering of human pluripotent stem cells (hPSCs) can enhance both basic and applied stem cell research. Adeno- associated virus (AAV) vectors are of particular interest for their capacity to mediate efficient gene delivery to and gene targeting in vari...

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Autores principales: Asuri, Prashanth, Bartel, Melissa A, Vazin, Tandis, Jang, Jae-Hyung, Wong, Tiffany B, Schaffer, David V
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277219/
https://ncbi.nlm.nih.gov/pubmed/22108859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.255
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