Peptide EphB2/CTF2 Generated by the γ-Secretase Processing of EphB2 Receptor Promotes Tyrosine Phosphorylation and Cell Surface Localization of N-Methyl-d-aspartate Receptors

Presenilin 1, a protein involved in the development of familial Alzheimer disease, is an important functional component of the γ-secretase complex that processes many cell surface receptors including the EphB2 tyrosine kinase receptors (Litterst, C., Georgakopoulos, A., Shioi, J., Ghersi, E., Wisnie...

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Bibliographic Details
Main Authors: Xu, Jindong, Litterst, Claudia, Georgakopoulos, Anastasios, Zaganas, Ioannis, Robakis, Nikolaos K.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Mechanisms of Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785649/
https://ncbi.nlm.nih.gov/pubmed/19661068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.048728
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