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Receptor-associated Protein Interacts with Amyloid-β Peptide and Promotes Its Cellular Uptake
Brain amyloid-β (Aβ) peptide accumulation and aggregation are critical events in the pathogenesis of Alzheimer disease. Increasing evidence has demonstrated that LRP1 is involved in Alzheimer disease pathogenesis. The physiological ligands of LRP1, including apoE, play significant roles in the cellu...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Biochemistry and Molecular Biology
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2785178/ https://ncbi.nlm.nih.gov/pubmed/19826010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.015032 |
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