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Twenty bone mineral density loci identified by large-scale meta-analysis of genome-wide association studies

Bone mineral density (BMD) is a heritable complex trait used in the clinical diagnosis of osteoporosis and the assessment of fracture risk. We performed meta-analysis of five genome-wide association studies of femoral neck and lumbar spine BMD in 19,195 subjects of Northern European descent. We iden...

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Main Authors: Rivadeneira, Fernando, Styrkársdottir, Unnur, Estrada, Karol, Halldórsson, Bjarni V., Hsu, Yi-Hsiang, Richards, J. Brent, Zillikens, M. Carola, Kavvoura, Fotini K., Amin, Najaf, Aulchenko, Yurii S., Cupples, L. Adrienne, Deloukas, Panagiotis, Demissie, Serkalem, Grundberg, Elin, Hofman, Albert, Kong, Augustine, Karasik, David, van Meurs, Joyce B., Oostra, Ben, Pastinen, Tomi, Pols, Huibert A.P., Sigurdsson, Gunnar, Soranzo, Nicole, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Williams, Frances MK, Wilson, Scott G., Zhou, Yanhua, Ralston, Stuart H., van Duijn, Cornelia M., Spector, Timothy, Kiel, Douglas P., Stefansson, Kari, Ioannidis, John P.A., Uitterlinden, André G.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783489/
https://ncbi.nlm.nih.gov/pubmed/19801982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.446
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