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Bivariate Genome-Wide Linkage Analysis of Femoral Bone Traits and Leg Lean Mass: Framingham Study

The risk of osteoporotic fracture is a function of both applied muscle mass and bone tissue distribution. Leg lean mass (LLM) and femoral bone geometry are both known to have substantial genetic components. Therefore, we estimated shared heritability (h(2)) and performed linkage analysis to identify...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Karasik, David, Zhou, Yanhua, Cupples, L Adrienne, Hannan, Marian T, Kiel, Douglas P, Demissie, Serkalem
Format: Artigo
Sprache:Inglês
Veröffentlicht: Amer Soc Bone & Mineral Res. 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659513/
https://ncbi.nlm.nih.gov/pubmed/19063671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.081222
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