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Bivariate Genome-Wide Linkage Analysis of Femoral Bone Traits and Leg Lean Mass: Framingham Study

The risk of osteoporotic fracture is a function of both applied muscle mass and bone tissue distribution. Leg lean mass (LLM) and femoral bone geometry are both known to have substantial genetic components. Therefore, we estimated shared heritability (h(2)) and performed linkage analysis to identify...

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Detalhes bibliográficos
Main Authors: Karasik, David, Zhou, Yanhua, Cupples, L Adrienne, Hannan, Marian T, Kiel, Douglas P, Demissie, Serkalem
Formato: Artigo
Idioma:Inglês
Publicado em: Amer Soc Bone & Mineral Res. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659513/
https://ncbi.nlm.nih.gov/pubmed/19063671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.081222
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