The rate of meiotic gene conversion varies by sex and age

Meiotic recombination involves a combination of gene conversion and crossover events that along with mutations produce germline genetic diversity. Here, we report the discovery of 3,176 SNP and 61 indel gene conversions. Our estimate of the non-crossover (NCO) gene conversion rate (G) is 7.0 for SNP...

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Publicado no:Nat Genet
Main Authors: Halldorsson, Bjarni V., Hardarson, Marteinn T., Kehr, Birte, Styrkarsdottir, Unnur, Gylfason, Arnaldur, Thorleifsson, Gudmar, Zink, Florian, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Sulem, Patrick, Masson, Gisli, Thorsteinsdottir, Unnur, Helgason, Agnar, Kong, Augustine, Gudbjartsson, Daniel F., Stefansson, Kari
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5083143/
https://ncbi.nlm.nih.gov/pubmed/27643539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3669
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