Biglycan, a Danger Signal That Activates the NLRP3 Inflammasome via Toll-like and P2X Receptors

The role of endogenous inducers of inflammation is poorly understood. To produce the proinflammatory master cytokine interleukin (IL)-1β, macrophages need double stimulation with ligands to both Toll-like receptors (TLRs) for IL-1β gene transcription and nucleotide-binding oligomerization domain-lik...

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Detalhes bibliográficos
Main Authors: Babelova, Andrea, Moreth, Kristin, Tsalastra-Greul, Wasiliki, Zeng-Brouwers, Jinyang, Eickelberg, Oliver, Young, Marian F., Bruckner, Peter, Pfeilschifter, Josef, Schaefer, Roland M., Gröne, Hermann-Josef, Schaefer, Liliana
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781998/
https://ncbi.nlm.nih.gov/pubmed/19605353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.014266
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