Biglycan-triggered TLR-2- and TLR-4-signaling exacerbates the pathophysiology of ischemic acute kidney injury

Exacerbated inflammation in renal ischemia-reperfusion injury, the major cause of intrinsic acute renal failure, is a key trigger of kidney damage. During disease endogenous danger signals stimulate innate immune cells via Toll-like receptor (TLR)-2 and -4 and accelerate inflammatory responses. Here...

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Autors principals: Moreth, Kristin, Frey, Helena, Hubo, Mario, Zeng-Brouwers, Jinyang, Nastase, Madalina-Viviana, Hsieh, Louise Tzung-Harn, Haceni, Riad, Pfeilschifter, Josef, Iozzo, Renato V., Schaefer, Liliana
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057019/
https://ncbi.nlm.nih.gov/pubmed/24480070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2014.01.010
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