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De novo expression of circulating biglycan evokes an innate inflammatory tissue response via MyD88/TRIF pathways
Matrix-bound constituents, such as the small leucine-rich proteoglycan biglycan, can act as powerful signaling molecules when released by limited proteolysis of the extracellular matrix or de novo synthesized by macrophages in the circulation and body fluids. Specifically, biglycan acts as an endoge...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4039567/ https://ncbi.nlm.nih.gov/pubmed/24361484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2013.12.003 |
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