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Nonsense-mediated mRNA decay mutes the splicing defects of spliceosome component mutations

The role of many splicing factors in pre-mRNA splicing and the involvement of these factors in the processing of specific transcripts have often been defined through the analysis of loss-of-function mutants in vivo. Here we show that inactivating the nonsense-mediated mRNA decay (NMD) results in an...

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Bibliografski detalji
Glavni autori: Kawashima, Tadashi, Pellegrini, Matteo, Chanfreau, Guillaume F.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779665/
https://ncbi.nlm.nih.gov/pubmed/19850912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1736809
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