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Regulation of Multiple Core Spliceosomal Proteins by Alternative Splicing-Coupled Nonsense-Mediated mRNA Decay

Alternative splicing (AS) can regulate gene expression by introducing premature termination codons (PTCs) into spliced mRNA that subsequently elicit transcript degradation by the nonsense-mediated mRNA decay (NMD) pathway. However, the range of cellular functions controlled by this process and the f...

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Hlavní autoři: Saltzman, Arneet L., Kim, Yoon Ki, Pan, Qun, Fagnani, Matthew M., Maquat, Lynne E., Blencowe, Benjamin J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447145/
https://ncbi.nlm.nih.gov/pubmed/18443041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00361-08
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