Quantitative microarray profiling provides evidence against widespread coupling of alternative splicing with nonsense-mediated mRNA decay to control gene expression

Sequence-based analyses have predicted that ∼35% of mammalian alternative splicing (AS) events produce premature termination codon (PTC)-containing splice variants that are targeted by the process of nonsense-mediated mRNA decay (NMD). This led to speculation that AS may often regulate gene expressi...

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Bibliografische gegevens
Hoofdauteurs: Pan, Qun, Saltzman, Arneet L., Kim, Yoon Ki, Misquitta, Christine, Shai, Ofer, Maquat, Lynne E., Frey, Brendan J., Blencowe, Benjamin J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2006
Onderwerpen:
Research Communications
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356107/
https://ncbi.nlm.nih.gov/pubmed/16418482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1382806
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