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Nonsense-mediated mRNA decay mutes the splicing defects of spliceosome component mutations
The role of many splicing factors in pre-mRNA splicing and the involvement of these factors in the processing of specific transcripts have often been defined through the analysis of loss-of-function mutants in vivo. Here we show that inactivating the nonsense-mediated mRNA decay (NMD) results in an...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2779665/ https://ncbi.nlm.nih.gov/pubmed/19850912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1736809 |
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