A Genome-Wide RNAi Screen for Modifiers of the Circadian Clock in Human Cells

Two decades of research identified more than a dozen clock genes and defined a biochemical feedback mechanism of circadian oscillator function. To identify additional clock genes and modifiers, we conducted a genome-wide siRNA screen in a human cellular clock model. Knockdown of nearly a thousand ge...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Zhang, Eric E., Liu, Andrew C., Hirota, Tsuyoshi, Miraglia, Loren J., Welch, Genevieve, Pongsawakul, Pagkapol Y., Liu, Xianzhong, Atwood, Ann, Huss, Jon W., Janes, Jeff, Su, Andrew I., Hogenesch, John B., Kay, Steve A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777987/
https://ncbi.nlm.nih.gov/pubmed/19765810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.08.031
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge