Spatiotemporal separation of PER and CRY posttranslational regulation in the mammalian circadian clock

Posttranslational regulation of clock proteins is an essential part of mammalian circadian rhythms, conferring sensitivity to metabolic state and offering promising targets for pharmacological control. Two such regulators, casein kinase 1 (CKI) and F-box and leucine-rich repeat protein 3 (FBXL3), mo...

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Bibliographic Details
Main Authors: St. John, Peter C., Hirota, Tsuyoshi, Kay, Steve A., Doyle, Francis J.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2014
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918757/
https://ncbi.nlm.nih.gov/pubmed/24449901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323618111
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