Photopharmacological Manipulation of Mammalian CRY1 for Regulation of the Circadian Clock

[Image: see text] CRY1 and CRY2 proteins are highly conserved components of the circadian clock that controls daily physiological rhythms. Disruption of CRY functions are related to many diseases, including circadian sleep phase disorder. Development of isoform-selective and spatiotemporally control...

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Udgivet i:J Am Chem Soc
Main Authors: Kolarski, Dušan, Miller, Simon, Oshima, Tsuyoshi, Nagai, Yoshiko, Aoki, Yugo, Kobauri, Piermichele, Srivastava, Ashutosh, Sugiyama, Akiko, Amaike, Kazuma, Sato, Ayato, Tama, Florence, Szymanski, Wiktor, Feringa, Ben L., Itami, Kenichiro, Hirota, Tsuyoshi
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2021
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863067/
https://ncbi.nlm.nih.gov/pubmed/33464888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c12280
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