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Interaction of circadian clock proteins PER2 and CRY with BMAL1 and CLOCK

BACKGROUND: Circadian oscillation of clock-controlled gene expression is mainly regulated at the transcriptional level. Heterodimers of CLOCK and BMAL1 act as activators of target gene transcription; however, interactions of PER and CRY proteins with the heterodimer abolish its transcriptional activ...

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Main Authors: Langmesser, Sonja, Tallone, Tiziano, Bordon, Alain, Rusconi, Sandro, Albrecht, Urs
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2383916/
https://ncbi.nlm.nih.gov/pubmed/18430226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-9-41
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