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Interaction of circadian clock proteins PER2 and CRY with BMAL1 and CLOCK
BACKGROUND: Circadian oscillation of clock-controlled gene expression is mainly regulated at the transcriptional level. Heterodimers of CLOCK and BMAL1 act as activators of target gene transcription; however, interactions of PER and CRY proteins with the heterodimer abolish its transcriptional activ...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2383916/ https://ncbi.nlm.nih.gov/pubmed/18430226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-9-41 |
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