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Posttranslational regulation of the mammalian circadian clock by cryptochrome and protein phosphatase 5

The molecular oscillator that drives circadian rhythmicity in mammals obtains its near 24-h periodicity from posttranslational regulation of clock proteins. Activity of the major clock kinase casein kinase I (CKI) ε is regulated by inhibitory autophosphorylation. Here we show that protein phosphatas...

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Bibliografiske detaljer
Main Authors: Partch, Carrie L., Shields, Katherine F., Thompson, Carol L., Selby, Christopher P., Sancar, Aziz
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502481/
https://ncbi.nlm.nih.gov/pubmed/16790549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604138103
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