Molecular mechanism of the repressive phase of the mammalian circadian clock

The mammalian circadian clock consists of a transcription–translation feedback loop (TTFL) composed of CLOCK–BMAL1 transcriptional activators and CRY–PER transcriptional repressors. Previous work showed that CRY inhibits CLOCK–BMAL1-activated transcription by a “blocking”-type mechanism and that CRY...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Cao, Xuemei, Yang, Yanyan, Selby, Christopher P., Liu, Zhenxing, Sancar, Aziz
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2021
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7812753/
https://ncbi.nlm.nih.gov/pubmed/33443219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2021174118
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