A Genome-Wide RNAi Screen for Modifiers of the Circadian Clock in Human Cells

Two decades of research identified more than a dozen clock genes and defined a biochemical feedback mechanism of circadian oscillator function. To identify additional clock genes and modifiers, we conducted a genome-wide siRNA screen in a human cellular clock model. Knockdown of nearly a thousand ge...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhang, Eric E., Liu, Andrew C., Hirota, Tsuyoshi, Miraglia, Loren J., Welch, Genevieve, Pongsawakul, Pagkapol Y., Liu, Xianzhong, Atwood, Ann, Huss, Jon W., Janes, Jeff, Su, Andrew I., Hogenesch, John B., Kay, Steve A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777987/
https://ncbi.nlm.nih.gov/pubmed/19765810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.08.031
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