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High-throughput Screening and Chemical Biology: New Approaches for Understanding Circadian Clock Mechanisms

Most organisms exhibit daily changes in physiology, behavior, and metabolism under the control of a cell-autonomous circadian clock. In the core clock mechanism, clock genes form a transcription factor network to generate circadian rhythms of gene expression. Phosphorylation of clock proteins and hi...

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Detalhes bibliográficos
Main Authors: Hirota, Tsuyoshi, Kay, Steve A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835411/
https://ncbi.nlm.nih.gov/pubmed/19778719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2009.09.002
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