Engineering of a novel hybrid enzyme: an anti-inflammatory drug target with triple catalytic activities directly converting arachidonic acid into the inflammatory prostaglandin E(2)

Lignende værker

• An active triple-catalytic hybrid enzyme engineered by linking COX-1 to prostacyclin synthase that can constantly biosynthesize prostacyclin, the vascular protector
  af: Ruan, Ke-He, et al.
  Udgivet: (2008)
• Large-scale expression, purification, and characterization of an engineered prostacyclin-synthesizing enzyme with therapeutic potential
  af: Ruan, Ke-He, et al.
  Udgivet: (2008)
• Screening and identification of dietary oils and unsaturated fatty acids in inhibiting inflammatory prostaglandin E(2) signaling in fat stromal cells
  af: Ruan, Diana, et al.
  Udgivet: (2012)
• A profile of the residues in the second extracellular loop that are critical for ligand recognition of human prostacyclin receptor
  af: Ni, Feng, et al.
  Udgivet: (2007)
• Characterization of the Prostaglandin H(2) Mimic: Binding to the Purified Human Thromboxane A(2) Receptor in Solution
  af: Ruan, Ke-He, et al.
  Udgivet: (2008)