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Inhibition of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in obstructive nephropathy

Activation of renal interstitial fibroblasts is critically involved in the development of tubulointerstitial fibrosis in chronic kidney diseases. In this study, we investigated the effect of trichostatin A (TSA), a specific histone deacetylase (HDAC) inhibitor, on the activation of renal interstitia...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Pang, Maoyin, Kothapally, Jagan, Mao, Haiping, Tolbert, Evelyn, Ponnusamy, Murugavel, Chin, Y. Eugene, Zhuang, Shougang
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Physiological Society 2009
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775583/
https://ncbi.nlm.nih.gov/pubmed/19640900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00282.2009
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