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Src inhibition blocks renal interstitial fibroblast activation and ameliorates renal fibrosis

Increased Src activity has been associated with the pathogenesis of renal tumors and some glomerular diseases, but its role in renal interstitial fibrosis remains elusive. To evaluate this, cultured renal interstitial fibroblasts (NRK-49F) were treated with PP1, a selective inhibitor of Src. This re...

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Podrobná bibliografie
Vydáno v:Kidney Int
Hlavní autoři: Yan, Yanli, Ma, Li, Zhou, Xiaoxu, Ponnusamy, Murugavel, Tang, Jinhua, Zhuang, Michelle A., Tolbert, Evelyn, Bayliss, Georgia, Bai, Jianwen, Zhuang, Shougang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824676/
https://ncbi.nlm.nih.gov/pubmed/26444028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2015.293
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