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Src inhibition blocks renal interstitial fibroblast activation and ameliorates renal fibrosis
Increased Src activity has been associated with the pathogenesis of renal tumors and some glomerular diseases, but its role in renal interstitial fibrosis remains elusive. To evaluate this, cultured renal interstitial fibroblasts (NRK-49F) were treated with PP1, a selective inhibitor of Src. This re...
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| 出版年: | Kidney Int |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4824676/ https://ncbi.nlm.nih.gov/pubmed/26444028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2015.293 |
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