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Src inhibition blocks renal interstitial fibroblast activation and ameliorates renal fibrosis
Increased Src activity has been associated with the pathogenesis of renal tumors and some glomerular diseases, but its role in renal interstitial fibrosis remains elusive. To evaluate this, cultured renal interstitial fibroblasts (NRK-49F) were treated with PP1, a selective inhibitor of Src. This re...
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| Vydáno v: | Kidney Int |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4824676/ https://ncbi.nlm.nih.gov/pubmed/26444028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2015.293 |
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