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Activation of Sirtuin-1 Promotes Renal Fibroblast Activation and Aggravates Renal Fibrogenesis

Although activation of sirtuin-1 (SIRT1) has been shown to protect the kidney from acute injury, its role in renal fibrosis remains controversial since both inhibition and activation of SIRT1 have been reported to attenuate renal fibrosis. To resolve this conflict, we further examined the effect of...

詳細記述

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書誌詳細
出版年:J Pharmacol Exp Ther
主要な著者: Ponnusamy, Murugavel, Zhuang, Michelle A., Zhou, Xiaoxu, Tolbert, Evelyn, Bayliss, George, Zhao, Ting C., Zhuang, Shougang
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Pharmacology and Experimental Therapeutics 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518074/
https://ncbi.nlm.nih.gov/pubmed/26022003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.224386
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