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Activation of Sirtuin-1 Promotes Renal Fibroblast Activation and Aggravates Renal Fibrogenesis

Although activation of sirtuin-1 (SIRT1) has been shown to protect the kidney from acute injury, its role in renal fibrosis remains controversial since both inhibition and activation of SIRT1 have been reported to attenuate renal fibrosis. To resolve this conflict, we further examined the effect of...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Pharmacol Exp Ther
Prif Awduron: Ponnusamy, Murugavel, Zhuang, Michelle A., Zhou, Xiaoxu, Tolbert, Evelyn, Bayliss, George, Zhao, Ting C., Zhuang, Shougang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Pharmacology and Experimental Therapeutics 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518074/
https://ncbi.nlm.nih.gov/pubmed/26022003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.224386
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