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Sustained Activation of EGFR Triggers Renal Fibrogenesis after Acute Kidney Injury

Severe acute kidney injury (AKI) is frequently accompanied by maladaptive repair and renal fibrogenesis; however, the molecular mechanisms that mediate these acute and chronic consequences of AKI remain poorly understood. In this study, we examined the role of epidermal growth factor receptor (EGFR)...

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Détails bibliographiques
Auteurs principaux: Tang, Jinhua, Liu, Na, Tolbert, Evelyn, Ponnusamy, Murugavel, Ma, Li, Gong, Rujun, Bayliss, George, Yan, Haidong, Zhuang, Shougang
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3702747/
https://ncbi.nlm.nih.gov/pubmed/23684791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.04.005
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