ERK pathway mediates P2X7 expression and cell death in renal interstitial fibroblasts exposed to necrotic renal epithelial cells

We recently reported that necrotic renal proximal epithelial cells (RPTC) stimulate the expression of P2X7 receptor in renal fibroblasts and that P2X7 receptor mediates deleterious epithelial-fibroblast cross talk. The present study was carried out to investigate the signaling mechanism of necrotic...

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Autores principales: Ponnusamy, Murugavel, Liu, Na, Gong, Rujun, Yan, Haidong, Zhuang, Shougang
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2011
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174556/
https://ncbi.nlm.nih.gov/pubmed/21677150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00215.2011
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