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ERK pathway mediates P2X7 expression and cell death in renal interstitial fibroblasts exposed to necrotic renal epithelial cells

We recently reported that necrotic renal proximal epithelial cells (RPTC) stimulate the expression of P2X7 receptor in renal fibroblasts and that P2X7 receptor mediates deleterious epithelial-fibroblast cross talk. The present study was carried out to investigate the signaling mechanism of necrotic...

詳細記述

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書誌詳細
主要な著者: Ponnusamy, Murugavel, Liu, Na, Gong, Rujun, Yan, Haidong, Zhuang, Shougang
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174556/
https://ncbi.nlm.nih.gov/pubmed/21677150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00215.2011
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