Genetic or Pharmacologic Blockade of EGFR Inhibits Renal Fibrosis

Although enhanced activation of the EGF receptor (EGFR) associates with the development and progression of renal fibrosis, the mechanisms linking these observations are not completely understood. Here, after unilateral ureteral obstruction (UUO), wild-type mice exhibited sustained EGFR phosphorylati...

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Detalhes bibliográficos
Main Authors: Liu, Na, Guo, Jian-Kan, Pang, Maoyin, Tolbert, Evelyn, Ponnusamy, Murugavel, Gong, Rujun, Bayliss, George, Dworkin, Lance D., Yan, Haidong, Zhuang, Shougang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2012
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338288/
https://ncbi.nlm.nih.gov/pubmed/22362908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011050493
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