Enhancer of Zeste Homolog 2 Inhibition Attenuates Renal Fibrosis by Maintaining Smad7 and Phosphatase and Tensin Homolog Expression

Enhancer of zeste homolog 2 (EZH2) is a methyltransferase that induces histone H3 lysine 27 trimethylation (H3K27me3) and functions as an oncogenic factor in many cancer types. However, the role of EZH2 in renal fibrogenesis remains unexplored. In this study, we found high expression of EZH2 and H3K...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Am Soc Nephrol
Main Authors: Zhou, Xiaoxu, Zang, Xiujuan, Ponnusamy, Murugavel, Masucci, Monica V., Tolbert, Evelyn, Gong, Rujun, Zhao, Ting C., Liu, Na, Bayliss, George, Dworkin, Lance D., Zhuang, Shougang
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2016
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926973/
https://ncbi.nlm.nih.gov/pubmed/26701983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015040457
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker