Genetic or Pharmacologic Blockade of EGFR Inhibits Renal Fibrosis

Although enhanced activation of the EGF receptor (EGFR) associates with the development and progression of renal fibrosis, the mechanisms linking these observations are not completely understood. Here, after unilateral ureteral obstruction (UUO), wild-type mice exhibited sustained EGFR phosphorylati...

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Bibliografiske detaljer
Main Authors: Liu, Na, Guo, Jian-Kan, Pang, Maoyin, Tolbert, Evelyn, Ponnusamy, Murugavel, Gong, Rujun, Bayliss, George, Dworkin, Lance D., Yan, Haidong, Zhuang, Shougang
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2012
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338288/
https://ncbi.nlm.nih.gov/pubmed/22362908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011050493
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