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Histone Deacetylase: A Potential Therapeutic Target for Fibrotic Disorders
Histone deacetylases (HDACs) are enzymes that balance the acetylation activities of histone acetyltransferases on chromatin remodeling and play essential roles in regulating gene transcription. In the past several years, the role of HDACs in cancer initiation and progression, as well as the therapeu...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society for Pharmacology and Experimental Therapeutics
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2967408/ https://ncbi.nlm.nih.gov/pubmed/20719940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.168385 |
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