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Histone Deacetylase: A Potential Therapeutic Target for Fibrotic Disorders

Histone deacetylases (HDACs) are enzymes that balance the acetylation activities of histone acetyltransferases on chromatin remodeling and play essential roles in regulating gene transcription. In the past several years, the role of HDACs in cancer initiation and progression, as well as the therapeu...

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Hlavní autoři: Pang, Maoyin, Zhuang, Shougang
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967408/
https://ncbi.nlm.nih.gov/pubmed/20719940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.168385
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