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Identification of histone deacetylase 8 as a novel therapeutic target for renal fibrosis

Histone deacetylases (HDACs) have been shown to alleviate renal fibrosis, however, the role of individual HDAC isoforms in this process is poorly understood. In this study, we examined the role of HDAC8 in the development of renal fibrosis and partial epithelial-mesenchymal transitions (EMT). In a m...

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Dades bibliogràfiques
Publicat a:FASEB J
Autors principals: Zhang, Yunhe, Zou, Jianan, Tolbert, Evelyn, Zhao, Ting C., Bayliss, George, Zhuang, Shougang
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7445474/
https://ncbi.nlm.nih.gov/pubmed/32281211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201903254R
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