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Identification of histone deacetylase 8 as a novel therapeutic target for renal fibrosis

Histone deacetylases (HDACs) have been shown to alleviate renal fibrosis, however, the role of individual HDAC isoforms in this process is poorly understood. In this study, we examined the role of HDAC8 in the development of renal fibrosis and partial epithelial-mesenchymal transitions (EMT). In a m...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Zhang, Yunhe, Zou, Jianan, Tolbert, Evelyn, Zhao, Ting C., Bayliss, George, Zhuang, Shougang
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7445474/
https://ncbi.nlm.nih.gov/pubmed/32281211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201903254R
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