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Identification of histone deacetylase 8 as a novel therapeutic target for renal fibrosis

Histone deacetylases (HDACs) have been shown to alleviate renal fibrosis, however, the role of individual HDAC isoforms in this process is poorly understood. In this study, we examined the role of HDAC8 in the development of renal fibrosis and partial epithelial-mesenchymal transitions (EMT). In a m...

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Détails bibliographiques
Publié dans:FASEB J
Auteurs principaux: Zhang, Yunhe, Zou, Jianan, Tolbert, Evelyn, Zhao, Ting C., Bayliss, George, Zhuang, Shougang
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7445474/
https://ncbi.nlm.nih.gov/pubmed/32281211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201903254R
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