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Selective inhibition of class IIa histone deacetylases alleviates renal fibrosis
In this study, we examined the effect of MC1568, a selective class IIa histone deacetylase (HDAC) inhibitor, on the development and progression of renal fibrosis in a murine model of renal fibrosis induced by unilateral ureteral obstruction (UUO). All 4 class IIa HDAC isoforms, in particular HDAC4,...
Gardado en:
| Publicado en: | FASEB J |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Federation of American Societies for Experimental Biology
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6593874/ https://ncbi.nlm.nih.gov/pubmed/30951378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201801067RR |
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