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Histone Methyltransferase EZH2: A Potential Therapeutic Target for Kidney Diseases

Enhancer of zeste homolog 2 (EZH2) is a histone-lysine N-methyltransferase enzyme that catalyzes the addition of methyl groups to histone H3 at lysine 27, leading to gene silencing. Mutation or over-expression of EZH2 has been linked to many cancers including renal carcinoma. Recent studies have sho...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Li, Tingting, Yu, Chao, Zhuang, Shougang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930071/
https://ncbi.nlm.nih.gov/pubmed/33679454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.640700
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