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Histone Methyltransferase EZH2: A Potential Therapeutic Target for Kidney Diseases
Enhancer of zeste homolog 2 (EZH2) is a histone-lysine N-methyltransferase enzyme that catalyzes the addition of methyl groups to histone H3 at lysine 27, leading to gene silencing. Mutation or over-expression of EZH2 has been linked to many cancers including renal carcinoma. Recent studies have sho...
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| Udgivet i: | Front Physiol |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7930071/ https://ncbi.nlm.nih.gov/pubmed/33679454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.640700 |
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