Transcriptional re-programming of primary macrophages reveals distinct apoptotic and anti-tumoral functions of IRF-3 and IRF-7

The immunoregulatory transcriptional modulators - interferon regulatory factor (IRF)-3 and IRF-7 possess similar structural features but distinct gene regulatory potentials. For example, adenovirus mediated transduction of the constitutively active form of IRF-3 triggered cell death in primary human...

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Detalhes bibliográficos
Main Authors: Goubau, Delphine, Romieu-Mourez, Raphaëlle, Solis, Mayra, Hernandez, Eduardo, Mesplède, Thibault, Lin, Rongtuan, Leaman, Douglas, Hiscott, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773157/
https://ncbi.nlm.nih.gov/pubmed/19152337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838832
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