Characterization of distinct molecular interactions responsible for IRF3 and IRF7 phosphorylation and subsequent dimerization

IRF3 and IRF7 are critical transcription factors in the innate immune response. Their activation is controlled by phosphorylation events, leading to the formation of homodimers that are transcriptionally active. Phosphorylation occurs when IRF3 is recruited to adaptor proteins via a positively charg...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Dalskov, Louise, Narita, Ryo, Andersen, Line L, Jensen, Nanna, Assil, Sonia, Kristensen, Kennith H, Mikkelsen, Jacob G, Fujita, Takashi, Mogensen, Trine H, Paludan, Søren R, Hartmann, Rune
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Gene regulation, Chromatin and Epigenetics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672473/
https://ncbi.nlm.nih.gov/pubmed/33205822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa873
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