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Characterization of distinct molecular interactions responsible for IRF3 and IRF7 phosphorylation and subsequent dimerization
IRF3 and IRF7 are critical transcription factors in the innate immune response. Their activation is controlled by phosphorylation events, leading to the formation of homodimers that are transcriptionally active. Phosphorylation occurs when IRF3 is recruited to adaptor proteins via a positively charg...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7672473/ https://ncbi.nlm.nih.gov/pubmed/33205822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa873 |
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