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TRAF6 and IRF7 Control HIV Replication in Macrophages
The innate immune system recognizes virus infection and evokes antiviral responses which include producing type I interferons (IFNs). The induction of IFN provides a crucial mechanism of antiviral defense by upregulating interferon-stimulated genes (ISGs) that restrict viral replication. ISGs inhibi...
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Hauptverfasser: | , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
Public Library of Science
2011
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3225375/ https://ncbi.nlm.nih.gov/pubmed/22140520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028125 |
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