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HIV Downregulates Interferon-Stimulated Genes in Primary Macrophages

HIV is able to outpace the innate immune response, including that mediated by interferon (IFN), to establish a productive infection. Primary macrophages, however, may be protected from HIV infection by treatment with type I IFN before virus exposure. The ability of HIV to modulate the type I IFN-med...

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Detalhes bibliográficos
Main Authors: Wie, Seong-Heon, Du, Pinyi, Luong, Tiffany Q., Rought, Steffney E., Beliakova-Bethell, Nadejda, Lozach, Jean, Corbeil, Jacques, Kornbluth, Richard S., Richman, Douglas D., Woelk, Christopher H.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573720/
https://ncbi.nlm.nih.gov/pubmed/23276142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2012.0052
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